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Supplier of Scilla Tablets 50mg & 100mg ,, Oral jelly, Tablets, Capsule from India
Scilla Tablets 50mg & 100mg
 
What is SCILLA Soft Tabs How It Was Discovered How Does Scilla Work Why Does It Work So Fast?
Required As The Pill Form Proper Dosage How Long Can Expect ? Age Factor
Clinical Studies Side Effects Precautions/Warnings Contraindicated
How Can Get ? Is Less Effective ? Combined With Other Treatment Of Ed In Women
What is SCILLA Soft tabs (sildenafil citrate)? : SCILLA or Sidenafil Citrate tablets are the first significant oral medication for the treatment of Erectile Dysfunction (ED). The medicine was originally developed as a cardiovascular medicine designed to improve blood flow in the vessels of the heart. However, during initial studies the medication was found to have a profound side effect. Individuals began to report a remarkable difference in their ability to achieve and maintain an erection. Further studies were completed and on March 27, 1998, the medication was approved by the FDA for the treatment of erectile dysfunction.
How it was (sildenafil citrate) discovered? : Sildenafil Citrate was originally developed by Pfizer® as a heart medication to improve blood flow by relaxing arteries. During these studies, it was found to be effective in increasing blood flow to the male genitals.
How Does Scilla (Sildenafil)® (Sidenafil Citrate) Work? : The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in corpus icavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.
Scilla Biotechnologies Ltd. Why Does Sildenafil Citrate Soft Tabs Work So Fast? : Absorption of Scilla (Sildenafil) tablets when taken in the traditional oral form is subject to the following :-
  • The ability of the medication to withstand the highly acidic environment of the stomach.
  • Gastric emptying time (which can be slowed by a fatty meal or the consumption of alcohol resulting in the maximum plasma concentrations occurring between one and four hours after consumption).
  • Time it takes to pass across the intestinal cell membranes
  • First Pass" metabolism by the liver, following the absorption in the small intestine, medications are passed to the liver via the portal vein. The liver subsequently changes the chemical compositions of medications forming metabolites, or changed chemical versions of the drug. As a part of this process a percentage of the active form of a medication may be deactivated. This is known as the "first pass" metabolism effect of the liver.
The specifically "compounded" Sidenafil Citrate sublingual lozenge bypasses the above outlined digestion processes allowing for the medication to be absorbed in a more efficient manner (the inside of the mouth is has dense supply of capillaries or small blood vessels that allow medications to cross easily into the blood). In fact, using the sublingual method of delivery the average dose of Scilla (Sildenafil) can be cut in half. Therefore, if you usually take a Scilla (Sildenafil) 50mg tablet you can split the 50mg Sildenafil Citrate lozenge in half and only take 25mg of the medication for a more pronounced effect.
Is The Same Dose Of Sidenafil Citrate Required As The Pill Form? : No, the sublingual method of delivery is more efficient; therefore, less of the medication is needed to achieve the desired effects.
What Is The Proper Dosage Of Sidenafil Citrate In The Sublingual Form? : Clinical trials have shown that for most men half of the normal dose of Scilla (Sildenafil)(sidenafil citrate) is sufficient to achieve the same positive effects as Scilla (Sildenafil) (sidenafil citrate). Therefore, most individuals can take half of the scored 50mg Sidenafil Citrate lozenge or a 25mg dose. Men should not consume more than one 50mg lozenge during any given 24 hour period.
How Will My Sidenafil Citrate Lozenges Be Shipped? : All orders are shipped in a discreet package with no hint of the contents.
How Long Before Intended Intercourse Should The Sidenafil Citrate Lozenge Be Used? : The Sidenafil Citrate Lozenges exert their action in a short period of time. Most men report a positive effect with 15 minute of the lozenge dissolving under the tongue.
Can The Sidenafil Citrate Lozenge Be Swallowed? :
The unique compounding of the Sidenafil Citrate lozenge were developed to be taken sublingually. Simply place the lozenge under the tongue for rapid absorption. Swallowing the lozenge will be of no benefit. In fact, the active ingredients will be degraded as outline above.
How Long Can I Expect My Erection To Last? Once an individual climaxes his erection will diminish per the norm or the individual may maintain the erection for a few more minutes. However, most men report a decrease in the refractory period (the time between climax and the next erection).
Is Age A Factor In The Effectiveness Of Sildenafil Citrate? : Actually, age does not seem to be a significant factor concerning the effectiveness of Sildenafil Citrate. In fact. many men experience erections that are as firm as they were when they in there early twenties. The erections tend to last longer and require less stimulation to stay erect secondary to the increased blood flow to the region.
What Clinical Studies Have Been Done? : Scilla (Sildenafil)® (sidenafil citrate) was administered to more than 3000 patients (age 19-87 years) with (ED) of various etiologies (organic, psychogenic or mixed) with a mean duration of 5 years. Scilla (Sildenafil)® (sidenafil citrate) demonstrated statistically significant improvement as compared to a placebo in all studies. In one particular study concerning the frequency of successful penetration during sexual activity and maintaining erection after penetration, 83% of these patients reported an improved erection on Scilla (Sildenafil)® (sidenafil citrate) verses 12% on a placebo medication.
What Happens If There Is No Sexual Stimulation Following The Sublingual Use Of The Sidenafil Citrate Lozenges? : Sildenafil Citrate is naturally eliminated from your body in a few hours.
What Are The Side Effects Of Sidenafil Citrate Lozenges? : The side effects are as one might expect the same as those reported with the Scilla (Sildenafil) (sidenafil citrate) tablets. Although side effects are rare and usually short short lived, some patients have reported the following side effects :
  • Congestion
  • Diarrhea
  • Facial Flushing
  • Headaches
  • Urinary Tract Infections
  • Visual Changes (mild and temporary changes in blue/green colors or increased sensitivity to light)
What Are Precautions/Warnings Concerning The Use Of Sublingual Sidenafil Citrate Lozenges? : Men who are taking medicines that contain nitrates (Nitroglycerin) of any kind must never use Sidenafil Citrate. Patients should not take Sidenafil Citrate even if you only take nitroglycerin medication occasionally. (Please see list of nitrates) There is also a potential for cardiac risk during sexual activity in patients with preexisting cardiovascular disease. Therefore, Sidenafil Citrate should not be used in men where sexual activity is inadvisable because of their underlying cardiovascular status. Several medications are known to interact with Sidenafil Citrate Therefore; one should inform their physician concerning all medications they are taking, including those medications acquired by a prescription as well as over the counter medicines. The use of Sidenafil Citrate offers no protection against sexually transmitted diseases, including HIV. Patients should continue to use protective measures necessary to guard against these diseases. In case of an overdose, call your physician immediately.
Can I Use Sidenafil Citrate Lozenges With Other Medications? : Yes, it is generally safe to use Sidenafil Citrate while on other medications. However some medicines may potentiate the effects of Sidenafil Citrate. Individuals should always consult with their healthcare provider prior to taking any medication. Note: Sidenafil Citrate does have one absolute contraindication; individuals who are taking medication-containing nitrate (even intermittently) should not take Sidenafil Citrate.
Why Is Sidenafil Citrate Lozenges Absolutely Contraindicated In Individuals Who Are Currently Taking Medications Containing Nitrates? : Sidenafil Citrate lhas been shown to potentate the hypotensive effects of nitrates to life threatening levels. Therefore, individuals who are currently using nitrates in any form even intermittently should not take Sidenafil Citrate. Nitrates are available in many medications; sprays, ointments, skin patches, pastes and tablets dissolved in the mouth. Nitrates are also found in illicit drugs such as amyl nitrate or nitrite "Poppers". If you are unsure if you are currently taking nitrates please value your health and consult with your local physician or pharmacist.
Can I Get Sidenafil Citrate Lozenges Over The Counter? :No, Sidenafil Citrate lozenges should only be taken by prescription from a licensed physician. FDA regulations do not permit Sidenafil Citrate lozenges to be taken without prescription. For a consultation for a Sidenafil Citrate lozenge prescription (click here). A Licensed Physician will review your medical history and patient profile. If approved for a Sidenafil Citrate lozenge prescription, we will have your order shipped discretely to your home or office in 1-2 business days.
For What Types Of ED Is Sidenafil Citrate Proving To Be Especially Effective? : Sidenafil Citrate is showing optimal results in individuals who experience Erectile Dysfunction secondary to high levels of anxiety (performance anxiety) and individuals with mild Erectile Dysfunction.
Is Sidenafil Citrate Less Effective In Treating Erectile Dysfunction That Is Secondary To Certain Underlying Medical Conditions? : This question is somewhat difficult to answer right now. More data is expected in the near future. Some initial data suggests that men, who have undergone radical prostatectomy (surgical removal of their prostate), using nerve-sparing procedures, are not achieving the same positive results with Sidenafil Citrate.
Can Sidenfal Citrate Lozenges Be Combined With Other Treatments For Erectile Dysfunction? : The use of such combined treatments is not recommended, since no clinical studies have been done to access Sidenafil Citrate safety and effectiveness.
Is There A Potential For Sidenafil Citrate To Be Used In The Treatment Of Ed In Women? : There are currently several medical research centers that are studying whether Sidenafil Citrate is a viable oral therapy for woman with sexual dysfunction. The problem is, secondary to anatomy, we know less concerning female sexual dysfunction than male sexual dysfunction. Historically, research has focused on male sexual dysfunction. Until we have a better understanding of the physiological processes causing erectile dysfunction in women are ability to treat the condition is limited. Although some physicians are prescribing Sidenafil Citrate to their female patients, it is important to note, the FDA has not approved the medication for the treatment of sexual dysfunction in women.
 
       
     
 
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